HISTOLOLOGICAL EFFECTS OF POMESTEEN POWER SUPPLEMENT ON THE LIVER OF ADULT WISTAR RATS

Ekundina, V.O and Ebeye, O.A. and Oladele, A.A. and Ajayi, M (2014) HISTOLOLOGICAL EFFECTS OF POMESTEEN POWER SUPPLEMENT ON THE LIVER OF ADULT WISTAR RATS. Journal of Pharmacology and Toxicology, 7 (1). pp. 8-16. ISSN 2141-4238

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HISTOLOLOGICAL-EFFECTS-OF-POMESTEEN-POWER-SUPPLEMENT-ON-THE-LIVER-OF-ADULT-WISTAR-RATS

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Abstract

Pomesteen power is a product of forever living product, a company known internationally for providing health services using herbs and other natural supplements. This study assessed the histological effects of pomesteen power drink on the liver of thirty (30) adult male wistar rats; the animals were randomly divided into five groups with six animals in each. Group 1 served as control while groups 2, 3, 4, 5, were test groups and received a daily dosage of 0.5ml, 1.0ml, 1.5ml and 2.0ml of pomesteen drink respectively for 30days. Following an overnight fast the animals were sacrificed, liver tissue harvested, fixed tissues were processed for routine paraffin sections and photomicrographs obtained. Results revealed a dose dependent reduction in liver weight that was not statistically significant however, histopathological findings showed mild congestion of the liver that was also dose dependent. In conclusion consumption of pomesteen power drink may be safe for consumption however functional studies are recommended in further studies to corroborate these findings.

Item Type: Article
Uncontrolled Keywords: pomesteen power, liver, histopathology and wistar rat
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: Mr Tayo Okunlola
Date Deposited: 15 May 2015 14:06
Last Modified: 15 May 2015 14:06
URI: http://eprints.abuad.edu.ng/id/eprint/104

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