Effec t Of Methanolic Extract of Vernonia Amygdalina on Haematological and Plasma Biochemical Parameters in Male Albino Rats

Oyedeji, K.O and Bolarinwa, A.F and Akintola, A.M (2013) Effec t Of Methanolic Extract of Vernonia Amygdalina on Haematological and Plasma Biochemical Parameters in Male Albino Rats. IOSR Journal of Dental and Medical Sciences ( IOSR - JDMS), 3 (5). pp. 64-67. ISSN 2279 - 0861

[img]
Preview
Text
4a9dda7294da3aa1a2e00f2476b1246d2bd8.pdf

Download (92kB) | Preview
Official URL: http://www.iosrjournals.org

Abstract

Vernonia amygdalina is a shrub that grows throughout tropical Africa. Several studies have reported the nutritional, anti - malaria and anti - helminthic effects of its extracts; but there is a dearth of information on its effect on blood chemistry. This study was des igned to investigate the effect of methanolic extract of Vernonia amygdalina (MEVA) on the haematological and plasma biochemical parameters in male albino rats. Treatment of rats for 30 days with all the treatment doses (50 mg/kg BW, 100 mg/kg BW, 150 mg/k g BW) of MEVA caused no significant (p>0.05) changes in all the haematological parameters (PCV, RBC, TWBC, Hb, MCHC, MCH, MCV, platelet, neutrophil, lymphocyte, eosinophil , monocyte) values relative to their respective controls. However , treatment of rats with 100 mg/kg BW and 150 mg/kg BW of MEVA caused significant (p<0.05) increase in albumen levels relative to the control. But treatment of rats with all the treatment doses of MEVA caused significant (p<0.05) decreased in ALT levels relative to the contro l. These findings suggest that methanolic extract of Vernonia amygdalina have beneficial potentialities on the blood of male albino rats.

Item Type: Article
Uncontrolled Keywords: Vernonia amygdalina, Red blood c ell , Total white blood c ell , Albino rats , Albumin .
Subjects: Q Science > Q Science (General)
R Medicine > R Medicine (General)
Divisions: Faculty of Medicine, Health and Life Sciences > School of Biological Sciences
Depositing User: Mr Tayo Okunlola
Date Deposited: 03 Jan 2018 14:26
Last Modified: 03 Jan 2018 14:26
URI: http://eprints.abuad.edu.ng/id/eprint/1381

Actions (login required)

View Item View Item