Phytochemical, Antimicrobial and Gc-Ms of African Nutmeg (Monodora Myristica).

Adewole, E and Ajiboye, B . O and Idris, O.O. and Ojo, O. A and Onikan, A and Ogunmodede, O.T and Adewumi, D.F (2013) Phytochemical, Antimicrobial and Gc-Ms of African Nutmeg (Monodora Myristica). Phytochemical, Antimicrobial and Gc-Ms of African Nutmeg (Monodora Myristica)., 2 (5). pp. 1-8. ISSN (Online): 2319 – 6718, (Print): 2319 – 670X

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Abstract

The quest to continue searching for new antibiotic, anti-parasites necitate this project as African nutmeg is a very useful plants medically and all its parts are useful. The major aim of this research work was to examine the monodora myristica for its secondary metabolites, antimicrobial analysis and to characterize the oil using gas chromatography mass spectrophotometer. The antimicrobial screening was done using agar method and the isolates used were obtained from the microbiology laboratory, Federal University of Technology, Akure, saponin, alkaloid, tannin and flavonoids were determined using standard methods. The results of the characterization of oil showed that organic compounds and fatty acids were present, the fatty acids present included, Palmitic acid, Eicosanoic acid, stearic acid, oleic acid, the results showed that the plants contained essential fatty acids useful for both adult and infant. The result of antimicrobial screening showed that the oil was very sensitive against the tested isolates. After 24hours incubation, the zone of inhibitions against Escherichia coli was (11millimetre), Bacillus substilis (8millimetre) and Staphylococcus aureus (11millimeter). The result compares favorably with standard streptomycin, the result of zone of inhibition against Escherichia coli of the sample (11millimetre) was better than that recorded for standard streptomycin (7millimetre).These may be as a result of presence various secondary metabolites which were discovered in the sample during analyses. These are flavonoids, tannin, saponin and alkaloids.

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