Correlation between Body Mass Index and Hematological Indices in Young Adult Nigerians with Different Hemoglobin Genotypes

Ajayi, Olutayo Ifedayo and Akinbo, David Bolaji and Okafor, Adaobi Mary-Joy (2017) Correlation between Body Mass Index and Hematological Indices in Young Adult Nigerians with Different Hemoglobin Genotypes. American Journal of Biomedical Sciences, 9 (1). pp. 1-10. ISSN 1937-9080

[img] Text
AJBMS_2017_1_05.pdf - Published Version

Download (411kB)
Official URL:


In view of the association of various haemoglobin electrophoretic patterns with different pathological conditions and obesity with its attendant risk factors for cardiac and pulmonary disorders, the present study evaluated the relationship between body mass index and haematological indices by randomly selecting young adult Nigerians with different haemoglobin electrophoretic patterns within the age group of 17-45 years and mean age of ±31 years old. 215 participants were enlisted for this study with their BMI and other anthropometric indices measured and grouped into different BMI categories as recommended by the World Health Organization. Haematological indices such as packed cell volume, total and differential white blood cell count, and platelets as well as haemoglobin (Hb) electrophoresis were assessed in relation to their anthropometric measurements using standard methods. We observed a significantly increased neutrophil and platelet counts in the subjects with BMI > 25 kg/m2. BMI was also observed to be positively correlated with the neutrophil, monocyte counts and MCV of haemoglobin AS and SS genotype groups in this study. This study showed a higher percentage of overweight and obesity among females, and haematological dyscrasias in mostly the HbSS subjects. Knowledge of the relationship between BMI and hematological indices of apparently healthy individuals within any population is therefore essential in healthcare planning, as a justification for early prognosis and genetic counselling policy strategically reducing the incidence of obesity, its attendant conditions and haemoglobinopathies in Nigeria.

Item Type: Article
Uncontrolled Keywords: Body Mass Index, Haematological indices, Haemoglobin Genotypes, Obesity, Leukocytosis
Subjects: Q Science > QP Physiology
R Medicine > R Medicine (General)
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: Mr. Victor Sebiotimo
Date Deposited: 03 Apr 2019 08:43
Last Modified: 03 Apr 2019 08:43

Actions (login required)

View Item View Item