Antioxidant enhancing ability of different solvents extractable components of Talinum triangulare in some selected Tissue homogenates of Albino Rats -In vitro

Afolabi, Olakunle Bamikole and Oloyede, Omotade Ibidun and Olayide, Isreal Idowu and i Obafemi, Tajudeen Olabis and Awe, Obabiolorunkosi Joseph and Afolabi, Blessing Ariyo and Onikani, Amos Sunday Antioxidant enhancing ability of different solvents extractable components of Talinum triangulare in some selected Tissue homogenates of Albino Rats -In vitro. Journal of Applied Pharmaceutical Science.

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Abstract

Antioxidant contents, mostly from plant source have been the major combating components against membranous peroxidation that causes degenerative diseases and among others in the living cells. In this work, we did look into how ethanol and aqueous extractable components of Talinum triangulare could effectively and synergistically enhance the activities of antioxidant enzymes i.e superoxide dismutase (SOD) catalase (CAT) and reduced glutathione (GSH) activities in the different tissues used in vitro. Different methods were employed in the assay and the results showed significant (p < 0.05) increase in ethanolic extract when the GSH enhancing competencies were considered in the organs when compare with that of aqueous and relatively with the control, also, the levels of catalase activities (CAT) observed showed significant (p < 0.05) difference as observed in the organs. Considering the superoxide dismutase (SOD) activities, aqueous extract showed significant (p < 0.05) increase in the liver and brain while significant (p < 0.05) increase was only observed in the ethanolic extract in the kidneys tissue. Indisputably, it could be claimed based on these facts that, Talinum triangulare could enhance the activities of these antioxidant enzymes assayed for and in turns could be helpful in the phytotherapeutic management of common diseases associated with the hypoactivity of the enzymes when involve in the diet.

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