Histo-morphometric Evidences for Testicular Derangement in animal models submitted to chronic and Sub-chronic Inhalation of Fragrance

Akunna, Gabriel G. and Saalu, Linus C. and Ogunlade, B. and AKINGBADE, A.M. and Anderson, Enye Linus and Olusolade, F.S (2015) Histo-morphometric Evidences for Testicular Derangement in animal models submitted to chronic and Sub-chronic Inhalation of Fragrance. American Journal of Research Communication, 3 (1). pp. 85-101. ISSN 2325-4076

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Abstract

Only few people are aware that in the manufacturing of a single bottle of perfume, about 600 individual chemical ingredients coined as fragrance are used. Exposure and a lingering culture of trade secrecy and undisclosed substances within the fragrance industry has remained an important factor when considering the hazardous and degenerative effect of these so called scents. In this study, we evaluated the histopathological effect of two popular perfumes used in Nigeria on the testis of rat. Sixty adult male Wistar rats were randomly divided into six groups of ten rats each. Group A and B rats (Controls) rats were exposed (6hrs day-1 ) to 5 ml kg-1 body weight of normal saline for 56 days and 112 days via whole body inhalation respectively, Group C and D rats were exposed (6hrs day-1 ) to 5 ml kg-1 body weight of one of the perfume designated as F1 for a period of 56 days and 112 days via whole body inhalation respectively while Group E and Group F rats were exposed (6hrs day-1 ) to 5 ml kg- 1 body weight of one of the perfume designated as F2 for a period of 56 days and 112 days via whole body inhalation respectively.

Item Type: Article
Uncontrolled Keywords: Fragrance, Testes, Stereology, Infertility, Oxidative Stress
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine
R Medicine > RG Gynecology and obstetrics
Divisions: Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User: Mr Tayo Okunlola
Date Deposited: 01 Jun 2016 10:07
Last Modified: 01 Jun 2016 10:07
URI: http://eprints.abuad.edu.ng/id/eprint/820

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